The anesthesia onset time was significantly less in group D2 Published by Elsevier Editora Ltda. After baseline measurements of mean arterial blood pressure and heart rhythm were taken, each patient received a 1. Efficacy and safety of dexmedetomidine infusion for patients undergoing awake craniotomy: Low dose ketamine decreases nociception by blocking NMDA receptor channels.

Postoperative analgesia requirement and sedation score were assessed. Anasthesiol Intensivmed Notfallmed Schmerzther. Dexmedetomidine -related polyuria in a pediatric patient. We report 4 of these cases that highlight our experience: Further studies in the use of dexmedetomidine for AFOI are warranted. We report a year-old male patient who presented to the Khoula Hospital, Muscat, Oman, in with a two month history of headaches and convulsions due to a space-occupying brain lesion in close proximity with the left motor cortex.

Mechanisms responsible for increased inflammatory response in Within the present review, an economic analysis of costs associated to the use of dexmedetomidine was therefore performed also in the Italian care setting.

intraoperative dexmedetomidine infusion: Topics by

The present study aims at comparing the hemodynamic, sedative, and analgesia potentiating effects of epidurally administered fentanyl and dexmedetomidine when combined with ropivacaine. Each patient in group A was administered with a bolus dose of dexmedetomidine 1.

Intraoperative SpO2 was higher in group D than in group S P Dexmedetomidine combined with sevoflurane for anesthesia for short burn surgery in children not only stabilize hemodynamic parameters but also reduce the impact to respiration. Standardized perioperative care protocols and reduced length of stay after colon surgery. The VNS at rest and after movement was significantly lower in group D at corresponding times except at 60 min throughout the assessment period.

A comparative study to evaluate the efficacy of dexmedetomidine as a hypotensive agent in comparison to esmolol in Functional Endoscopic Sinus Surgery FESS.


Pediatric awake craniotomy for seizure focus resection with dexmedetomidine sedation-a case report. We did not observe respiratory depression in any of the patient from either group. To compare the presence or absence of pain, pain-related behavioral responses, and hormonal responses to noxious stimuli during standing laparoscopic ovariectomy in mares sedated with continuous intravenous IV detomidine infusion and caudal epidural detomidine.

Patients were monitored for hemodynamics, recovery time and complications.

dexmedetomidine thesis topics

Patients with normal renal function and scheduled for elective CABG were randomized to placebo or to infusion of dexmedetomidine to achieve a pseudo steady-state plasma concentration of 0. Dexmedetomidine is a potentially useful medication demedetomidine the targeted treatment of intractable pain and delirium in the tertiary palliative care environment.

Choosing a Thesis Topic – SMS Anaesthesia Thesis Centre

To validate the efficacy and cost fhesis associated with pharmacy-driven dexmedetomidine appropriate use topisc and stewardship in mechanically ventilated patients. Comparison of CSF dynamics in 26 patients studied by infusion cisternography and conventional cisternography showed similar patterns, suggesting no alteration of CSF dynamics by the artificial CSF infusion.

We hypothesised that a single-dose of dexmedetomidine would reduce emergence agitation in adults with nasotracheal intubation after orthognathic surgery.

DEX also significantly decreased dexmedetomidjne levels of free radicals on ischemia-reperfusion injury of epigastric island flaps of rats [ 21 ] and ischemic rat hippocampus [ 22 ]. Furthermore, we observed that the beneficial effect of dexmedetomidine treatment following CPB was associated with a reduction in IL6, an inflammatory cytokine in plasma and cortex.

Nevertheless, prospective randomized trials are necessary to confirm the optimal anesthetic technique to be used.

Future research is required to compare dexmedetomidine infusion to standard treatment with midazolam infusion for treatment of intractable symptoms in the palliative care environment.

Epidural dexmedetomidine is comparable to epinephrine as an adjuvant to epidural lidocaine in fastening the onset of surgical anesthesia and resulted in better intraoperative analgesia and in longer duration of sensory and motor block in the settings of converting labor epidural analgesia for emergency CS. Published by Elsevier Editora Ltda. A questionnaire regarding the patient’s feelings of the management of sedation was taken from each patient and was also filled out by the surgeon.


The presence of shivering was assessed by a blinded observer after the completion of subarachnoid drug injection.

All patients were assessed intra-operatively for bleeding at surgical field, haemodynamic changes, awakening time and post-operative recovery. Full Text Available Background: Gynaecological, Orthopaedic or Specific surgery tyesis.

Oxidative Medicine and Cellular Longevity

Fourteen patients required interventions for adverse events. The anesthetic management of adolescents undergoing bariatric surgery presents a number of challenges, including increased risk of postoperative opioid-related respiratory depression. To receive news and publication updates for Oxidative Medicine and Cellular Longevity, enter your email address in the box below.

The average operation time was 50 min, and Group M had a higher number of prolonged surgeries.

dexmedetomidine thesis topics

Dexmedetomidine has anesthesia-sparing effects, dexmmedetomidine decreases MAP, HR and with reasonable analgesic effect. Effects of dexmedetomidine on microregional O2 balance during reperfusion after focal cerebral ischemia. The plasma high-mobility group box 1 level decreased significantly from Patients were assigned into three groups — 1 Group D0.

Dexmedetomidine pretreatment significantly reduced hyperoxia-induced neurodegeneration in different brain regions of the neonatal rat.